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Expert prediction

NFL Week 16: New England Patriots vs. Baltimore Ravens Preview, Odds, Picks (Dec 21)

  • Nikola Velickovic
  • Dec 18, 2025 at 4:06 AM EST

Pick rationale

Analysis & key factors

  • Patriots vs. Ravens odds favor Baltimore by 3 points.
  • The TOTAL went OVER in 6 of New England’s last 8 games.
  • Ravens are 1-4 ATS in the last 5 events.

This one might have a huge impact on the AFC playoff picture, as both teams chase their division titles.

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How to Watch

  • When: Sunday, December 21, 8:20 pm ET
  • Where: M&T Bank Stadium, Baltimore, Maryland
  • How to Watch: NBC, Peacock

Patriots vs. Ravens Odds

TeamMoneylineSpreadTotals
Patriots+135+348.5
Ravens-165-348.5

Game Preview

The New England Patriots lost to the Bills at home last week 35-31, which was a huge setback to their playoff plans. They need to keep winning to hold onto the top spot in the AFC East and hope for other results to go their way to take the top seed in the AFC.

Drake Maye had his worst game of the year, tossing only 155 passing yards without any touchdowns and one pick. He did run for two scores, the same as fantastic TreVeyon Henderson, who had 148 rushing yards.

The Baltimore Ravens jumped back into the saddle after back-to-back losses to the Bengals and the Steelers, with a big win over Joe Burrow and the Bengals, 24-0.

Alohi Gilman had an 84-yard pick-six, while Lamar threw for two touchdown passes, one to Rasheen Ali and the other to Zay Flowers. Baltimore ran for 189 yards.

Patriots vs. Ravens Head to Head

In 16 games, including 4 postseason matches, the Pats have 11 wins and the Ravens 5.

Patriots vs. Ravens Predictions

This will be an interesting game here, but we give the edge to the Pats, due to their better defense, one of the strongest in the NFL. Both teams have a solid offense, but the edge here will be New England’s defense.

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