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Expert prediction

NFL Week 16: New York Jets vs. New Orleans Saints Preview, Odds, Picks (Dec 21)

  • Nikola Velickovic
  • Dec 16, 2025 at 5:27 PM EST

Pick rationale

Analysis & key factors

  • Jets vs. Saints odds favor New Orleans at -220.
  • The TOTAL went OVER in 5 of the Jets’ last 7 games.
  • New Orleans Saints are 4-1 ATS in the past 5 games.

The Saints have found their QB, Tyler Shough, and need to develop him now. That’s something the Jets don’t have and will have to look for in the upcoming draft.

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How to Watch

  • When: Sunday, December 21, 1 pm ET
  • Where: Caesars Superdome, New Orleans, Louisiana
  • How to Watch: CBS

Jets vs. Saints Odds

TeamMoneylineSpreadTotals
Jets+180+4.540.5
Saints-220-4.540.5

Game Preview

The Jets lost the last two games heavily. The first was to the Dolphins at home, 34-10, and then came the defeat to the Jaguars, 48-20, in Florida. It was a really nasty experience for Aaron Glen and his unit. To be honest, more and more fans are asking whether he is really suited for the head coaching position.

NYJ’s games are efficient, and 5 of the past 7 have gone OVER the set total. Thought that’s mostly due to their disastrous defense, one of the worst in the NFL.

The Saints have back-to-back wins, both against division rivals competing for the NFC South title and a playoff spot. So, that’s how good the Saints are right now. Tyler Shough is their starting QB for the moment, and apparently, he could become a permanent solution.

He had two rushing touchdowns against the Buccaneers on the road in the 24-20 victory, and on the other hand, he was poised and focused against the Panthers at home. In a 20-17 triumph, Shough had 272 passing yards for one TD pass.

Jets vs. Saints Head to Head

There were 14 matches so far. The Saints have 8 wins and the Jets 6.

Jets vs. Saints Predictions

Undoubtedly, the Saints are in a better form right now and look like a better team. Plus, they play at home, which is an additional plus for this unit.

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