Expert prediction
NFL Week 2: Broncos vs. Colts Preview, Odds, Picks (Sep 14)
- Nikola Velickovic
- Sep 9, 2025 at 11:24 AM EDT
Pick rationale
Analysis & key factors
- Broncos vs. Colts total points line is set at 42.5 points.
- Denver Broncos limited the Titans to 133 yards in total last week.
- Daniel Jones ran for two touchdowns against the Dolphins.
Danny Dimes madness has overwhelmed Indianapolis. We can’t imagine what will happen if he leads the Colts to a win over the Broncos.
If you want more NFL odds and predictions, please follow this link.
How to Watch
- When: Sunday, September 14, 4:05 pm ET
- Where: Lucas Oil Stadium, Indianapolis, Indiana
- How to Watch: CBS
Broncos vs. Colts Odds
Game Preview
Bo Nix didn’t have a good performance against the Titans, completing 176 passing yards, one touchdown pass, and two interceptions. He even had a lost fumble, which, overall, should worry the Broncos’ fans.
However, the defense covered up all that. The Denver Broncos sacked Cam Ward 6 times, each time by a different defender. Hosts posted 12 QB hits, with Nik Bonitto posting three, as well as Zach Allen.
S/O to this defense 😤 pic.twitter.com/nB0fhal2Nm
— Denver Broncos (@Broncos) September 8, 2025
The Colts trashed the Miami Dolphins 33-8. QB Daniel Jones threw for 272 passing yards, having one TD pass. Yet that wasn’t his most significant achievement on Sunday. Danny Dimes ran for 2 touchdowns and emerged as the x-factor here.
Jonathan Taylor rushed 18 times for 71 yards, Michael Pittman Jr. had 80 receiving yards and one touchdown, and Tyler Warren had 76 receiving yards. Eventually, the Colts had almost twice as many total yards as the Dolphins, 418 to 211.
Broncos vs. Colts Head to Head
The overall score between these two teams is tied at 15 wins each. We’ve seen them play last season, when Denver beat the Colts 31-15 at the Mile High.
Broncos vs. Colts Predictions
The Denver Broncos have a terrifying defense, but on the other side, their quarterback still oscillates. That’s the sole reason why we give the Colts an edge in this one. Jones and the versatile offense, the Colts will go toe to toe with the Broncos’ defense, but on the other hand, Nix will have plenty of problems to find his rhythm.
- Free NFL picks: Colts win
NFL
More Predictions
NFL Week 9 Upsets: Commanders Nasty Underdogs, Cardinals and Raiders Defending the Spread
Week 9 of the 2026 NFL season features several situational spots where short underdogs hold tactical, scheduling, or matchup advantages. There aren’t as many choices as in previous rounds, but there’s still enough for us bettors to make some money. Here is one straight-up upset pick and two point-spread underdog picks, backed by key tactical […]
NNikola Velickovic 3 min read
NFL Week 9 Player Props: Pitts to Score a TD, Flournoy Continues to Grow
NFL Week 9 player props are here. We’ve waited to see the situation regarding potential absences and injuries, and with game day just around the corner, it was time to unleash the best player prop picks for this round. We have three selections for our bettors, carefully picked and evaluated following a thorough process. After […]
NNikola Velickovic 2 min read
Broncos vs. Panthers Week 9 Picks: Young’s Poor Protection Will Cost Carolina
Best bet: Broncos ATS pick: Broncos -2.5 Bet Broncos vs. Panthers at BetUS Denver Broncos (6-2) hit the road to face the Carolina Panthers (3-4) and continue their excellent run. The Panthers have been on the downhill lately and are under pressure to win this game and get back to the winning side. Stay with […]
NNikola Velickovic 2 min read
Giants vs. Eagles Week 9 Picks: Rested Giants After a Win in Philly
Best bet: Giants ATS pick: Giants -3.5 Bet Giants vs. Eagles at BetUS NFC East is completely wild these days. The New York Giants (4-2-1) lead the group, while the Philadelphia Eagles (2-6) sit last. The home team is in huge trouble, having multiple stars out due to injuries. The Giants also have some absences, […]
NNikola Velickovic 2 min read
Browns vs. Saints Week 9 Picks: Indoor Arena Will Create Problems for Cleveland
Best bet: Saints -1.5 Straight up pick: Saints moneyline Bet Cardinals vs Cowboys at BetUS Cleveland Browns (5-3) are still in the mix for the playoffs. However, they will need to win in New Orleans against the Saints (2-5). Browns are very light underdogs here, sitting at +100 before we started writing this article. We […]
NNikola Velickovic 2 min read