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Expert prediction

NFL Week 3: Lions vs. Ravens Preview, Odds, Picks (Sep 22)

  • Nikola Velickovic
  • Sep 17, 2025 at 11:05 AM EDT

Pick rationale

Analysis & key factors

  • Lions vs. Ravens is the NFL Week 3 Monday Night Football.
  • Ravens are 4.5-point favorites.
  • Both teams have a 1-1 record.

Monday Night Football will be electric, as the Lions visit the Ravens. These two teams have lethal offenses, and we hope to see some fireworks at the M&T Bank Stadium.

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How to Watch

  • When: Monday, September 22, 8:15 pm ET
  • Where: M&T Bank Stadium, Baltimore, Maryland
  • How to Watch: ABC, ESPN

Lions vs. Ravens Odds

TeamMoneylineSpreadTotals
Lions +200+4.552.5
Ravens-240-4.552.5

Game Preview

Lions lost the opener to the Packers, yet immediately bounced back, beating another NFC North rival, the Chicago Bears, 52-21. The entire team was in perfect rhythm, posting 511 yards. Goff threw for 334 yards and 5 touchdowns, three of which went to Amon-Ra St. Brown, who had 113 receiving yards.

Jameson Williams had 108 in two catches and a TD, while the rushers posted 177 yards on the ground. Jahmyr Gibbs had 94 and a score, while David Montgomery had 57 and also a score.

Ravens recovered following a tough loss in Buffalo by beating the Cleveland Browns, 41-17. They would slice through the Browns’ defense like a knife through butter, with Lamar throwing for 4 touchdowns and 225 yards.

Believe it or not, the Ravens ran for only 45 yards in this one. We can’t remember a game with them having this low run productivity. Roquan Smith had a pick-six, and he also managed to hit Flacco twice in this event.

Lions vs. Ravens Head to Head

There have been only 7 games between these two teams, and the Ravens lead 6-1. Last one was in 2023, 38-6 for the Ravens in Baltimore.

Lions vs. Ravens Head to Head

Detroit is excellent on the offensive side, and so is Baltimore. The only pick we are after here is OVER 52.5 points. The Lions scored 65 points in two events, and the Ravens 81. Enough said.

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