Expert prediction
NFL Week 5: Buccaneers vs. Seahawks Preview, Odds, Picks (Oct 5)
- Nikola Velickovic
- Oct 1, 2025 at 5:23 AM EDT
Pick rationale
Analysis & key factors
- Buccaneers vs. Seahawks odds favor Seattle at -190.
- Tampa Bay’s RB Bucky Irving will probably miss this game.
- Seattle Seahawks allow the 2nd fewest number of points in the NFL, 16.8 ppg.
The Bucs are banged up, and they are heading for Seattle to meet the in-form Seahawks, who have been showing off very good football this season.
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How to Watch
- When: Sunday, October 5, 4:05 pm ET
- Where: Lumen Field, Seattle, Washington
- How to Watch: CBS
Buccaneers vs. Seahawks Odds
Game Preview
The Buccaneers were ripped off with some of the calls against the Eagles; we won’t lie there. Tampa Bay was maybe even supposed to win this event, but in the end, it was 21-25 for the champions.
Now, apart from losing the game, they lost several players due to injuries, the most important being their running back, Bucky Irving. Besides him, WR Mike Evans is out as well, which is a huge hit for the offense. Therefore, the defense will have to step up in this one.
Rookie IOL Grey Zabel ranks 2nd in Run Block Win Rate among ALL offensive linemen.
— Seahawks Today (@TodaySeahawks) September 30, 2025
He ranks FIRST among all interior offensive linemen. pic.twitter.com/C2czPilXOx
Mentioning defense, Seattle’s is one of the best in the league. They allow only 16.8 points per game, which is the second-fewest in the NFL, and are allowing 89.8 yards on the ground. Right now, Mike Macdonald’s boys have three wins in a row, the most recent on the road in Arizona, 23-20.
The Seahawks sacked Kyler Murray six times in this game and intercepted him twice. Additionally, Seattle’s defense hit him seven times, showcasing monster power on the defensive side.
Buccaneers vs. Seahawks Head to Head
In 15 games so far, the Seahawks have recorded 9 wins, while Tampa Bay has 6.
Buccaneers vs. Seahawks Predictions
All the injuries are too much for the Bucs, who are now facing one of the hardest teams in the NFL, on the road. Do remember that Lumen Field stands as one of the most hostile places for playing; therefore, betting on the Seahawks here would be a smart choice.
- Free NFL picks: Seahawks Win
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