Expert prediction
NHL: Senators vs. Sabres Picks, Odds, and Preview (Oct 15)
- Alex Dudley
- Oct 14, 2025 at 6:22 AM EDT
Two sides that have endured challenging starts to the new NHL season will lock horns at KeyBank Center on Oct 15. The Buffalo Sabres will be aiming to end their losing streak at the start of the campaign, while the Ottawa Senators will be hoping to get their form back on track.
Event Overview
- When: Wednesday, October 15, 2025. 7:00 PM ET
- Where: KeyBank Center, Buffalo
- How to Watch: ESPN+
Senators vs. Sabres Odds
Head-to-Head Record
The Sabres will have the advantage at KeyBank Center on Wednesday after winning 55% of their home games against the Senators. Meanwhile, the Sabres have won each of the last seven head-to-head meetings between the teams.
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Match Preview
There will be increased pressure on Lindy Ruff and the Buffalo Sabres this week, as they play for the second straight game at the KeyBank Center. The Sabres have fallen to defeats in each of their opening three games in the NHL this season, and there will be a desperate need to get their performance levels back on track.
Buffalo were last in action on Monday, as they were easily beaten by the Colorado Avalanche. Despite scoring in the opening period, the Sabres looked weak offensively throughout the duration of the game. Their only bright spark was the goal by Tage Thompson.
The Ottawa Senators will be the visitors to Buffalo this week, as they chase a second win of the season. Ottawa have suffered two defeats already this term, which includes a recent loss at the hands of the Nashville Predators.
The Senators looked short of ideas in the offensive areas throughout that clash, with their only goal being scored in the final frame. It was a night to forget for goalie Linus Ullmark, who allowed two goals from the 24 shots that he faced.
Senators vs. Sabres Picks
Both of these teams will have a point to prove following recent losses in the NHL. However, the head-to-head record could be challenging to overlook. Therefore, the preference is for a home win when making Senators vs. Sabres picks.
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