NFL Odds, Predictions: Titans vs. Giants Week 3 Preview & Picks (Sep 27)

By · Updated 2 minutes ago
  • Titans vs. Giants odds heavily depend on Jaxson Dart’s condition.
  • Giants’ QB picked up an injury against the Rams on his 7th snap.
  • Titans are 0-2 at the moment.

Jaxson Dart injured his knee against the Rams, and bookmakers are waiting to see whether he will play this weekend before locking in the odds. As for the Titans, they are winless and hope for a miracle in the Big Apple.

Check for more NFL odds and picks here.

How to Watch

  • When: Sunday, September 27, 2026, 1:00 PM ET
  • Where: MetLife Stadium, East Rutherford, New Jersey
  • How to Watch: CBS

Titans vs. Giants Odds

TeamMoneylineSpreadTotals
Titans+150+3.545.5
Giants-180-3.545.5

Game Preview

Titans (0-2) gave their best effort against the Eagles but suffered a narrow 24-20 defeat. They were even up at one point in the fourth period, but didn’t have the offensive consistency to rebuff Philly’s attack.

Sophomore quarterback Cam Ward was good, ending the day with 183 passing yards and 7 rushing yards on two attempts. Still, on those two runs, Ward carried the ball into the end zone twice. We also need to mention Amani Hooker’s 92-yard pick-six.

Jaxson Dart is injured, and that’s the most important thing for the Giants (1-1) now. The 28-6 loss to the Rams in LA isn’t as painful as the fact that they might be without their team anchor in the coming period.

The pressure is now on veteran Jameis Winston. The 32-year-old has a chance to prove his worth again and deliver some of his magic. Though, we haven’t seen anything in LA, where he passed for 111 yards and was picked off once.

Titans vs. Giants Predictions

Skattebo, Singletary, and Najee Harris will have to improve the run game against the Titans. Tennessee’s defense is improving, though the offense still isn’t that consistent. As we see it, defenses will dominate on the field, and there will be plenty of running. All this suggests betting the under.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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