Expert prediction
Champions League: Tottenham vs. Villarreal Picks, Odds, and Preview (Sep 16)
Pick rationale
Analysis & key factors
Tottenham Hotspur make their return to the Champions League this week after winning the Europa League in 2024-25. Thomas Frank will be hopeful of maintaining his excellent start to life at Spurs when they come up against Villarreal on matchday one on Sep 16. You can find the odds and our picks here.
How To Watch
- When: Tuesday, September 16, 2025, at 3:00 PM ET
- Where: Tottenham Hotspur Stadium, London, England
- How To Watch: CBS
Tottenham vs. Villarreal Odds
Head-to-Head Record
Tottenham and Villarreal will collide for the first time in a competitive fixture this week.
Match Preview
It has been an excellent start to life at Tottenham for Thomas Frank, and confidence levels within the camp should be high following an excellent victory against West Ham United on Saturday. However, Spurs have an underwhelming record against Spanish teams, having won just one of their last 13 clashes with La Liga clubs.
Tottenham have also traditionally been slow starters in the Champions League, winning on matchday one in just two of their last seven appearances. But, it could be worth noting that the two wins that they have recorded have come in home matches, which bodes well for this clash on Tuesday.
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Villarreal have made an impressive start to the new La Liga season, winning two of their four matches. However, a return to form will be required on Tuesday after losing against Atletico Madrid in their latest outing. The Spanish side will be playing in the Champions League for the first time since 2021-22.
Villarreal have a below-par record against English teams, having failed to win in their last 14 clashes. It could also be worth noting that the Spanish side have lost their last seven fixtures against Premier League teams.
Tottenham vs. Villarreal Picks
It has been an excellent start to life in North London for Thomas Frank, and a win on MD1 in the Champions League would continue the momentum. However, Villarreal could be overlooked in the betting this week after their reliable start to the campaign, meaning that the narrow preference is for the draw.
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