MLS Predictions: Best Bets, Odds & Picks For This Weekend (Oct 10-11)

MLS action resumes following the international break this weekend, as the battle for important points in the race for playoff spots across the Eastern and Western Conferences heat up. An all-Canadian clash is set for BMO Field as Toronto host CF Montreal, while the Seattle Sounders travel to the New England Revolution. You can find our soccer predictions for every fixture this weekend and our MLS best bets here.

MLS Best Bets For This Weekend & Top Value Picks

• Best Pick: Inter Miami (vs. D.C. United)
• Best Both Teams to Score (BTTS): Orlando City vs. Columbus Crew
• Best Value Over/Under: Colorado Rapids vs. San Jose Earthquakes (Over 2.5 Goals)

ALSO SEE: Breeders’ Cup Classic Picks, Odds, Leading Contenders, Betting Insights & Analysis

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Key Fixture Breakdown & Best Bets

New England Revolution vs. Seattle Sounders Prediction & Odds

Kickoff: Saturday, October 10 | 6:30 PM ET | Gillette Stadium, Foxborough

Match Preview

A pivotal clash with implications for both the Eastern and Western Conferences is set for Gillette Stadium on Saturday evening. The New England Revolution have climbed to second in the East after winning three of their last four.

Meanwhile, the Seattle Sounders have re-emerged as a Western playoff hopeful after winning three on the bounce.

The consistent nature of the Sounders should be respected this weekend, as they have avoided defeat in eight, with five draws being played out over that period. For that reason, a draw could be among the interesting MLS picks to consider this weekend.

• Best Bet: The Draw (+290)

Atlanta United vs. FC Cincinnati Prediction & Odds

Kickoff: Saturday, October 10 | 7:30 PM ET | Mercedes-Benz Stadium, GA

Match Preview

All of the pressure will be on FC Cincinnati when they travel to the Mercedes-Benz Stadium on Saturday, as the club have dropped out of the playoff spots after failing to win in their last six.

In fact, Cincinnati have suffered three defeats in their previous five. Atlanta United’s season has ultimately been a disappointment, but confidence can be gained after going three without defeat.

A much better defensive record is notable across that period, with Atlanta keeping clean sheets in two fixtures. Cincinnati’s record on the road is concerning, winning just one of their 14. Therefore, a potential upset is hard to overlook.

• Best Bet: Atlanta United (+130)

Sporting KC vs. Portland Timbers Prediction & Odds

Kickoff: Saturday, October 10 | 8:30 PM ET | Sporting Park, KS

Match Preview

Sporting Kansas City have been one of the biggest disappointments in the MLS this season, as they sit rock-bottom of the Western Conference. They come into this round after winning two of their last four, but they have suffered defeats in five of their previous seven.

The Portland Timbers will have a greater need for victory on Saturday, as they sit four points adrift of the playoff spots. A concern would be their recent results, as the Timbers have lost three on the bounce.

However, it’s notable that the Timbers have a strong road record against Sporting KC, avoiding defeat in eleven of their last 17 at Sporting Park.

• Best Bet: Portland Timbers (+160)

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MLS Best Parlay Bets This Weekend

You can generate returns on MLS picks this weekend by combining multiple legs into a parlay. Short-priced home wins for Inter Miami, LAFC, and St. Louis SC should create a platform for bettors. Meanwhile, the Colorado Rapids and Charlotte FC should get the better of their respective rivals, the San Jose Earthquakes and FC Dallas.

• Best MLS Parlay Bet: Inter Miami, LAFC, St. Louis SC, Colorado Rapids & Charlotte FC All To Win

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MLS Best Bets For All Matches This Weekend

Date	Matchup	Kick-Off	Pick
Sat, Oct 10	Toronto FC vs. Montreal	1:00 PM ET	Toronto FC
Sat, Oct 10	Chicago Fire vs. NYCFC	2:30 PM ET	The Draw
Sat, Oct 10	New England Revolution vs. Seattle Sounders	6:30 PM ET	The Draw
Sat, Oct 10	Inter Miami vs. D.C. United	7:30 PM ET	Inter Miami
Sat, Oct 10	Philadelphia Union vs. Real Salt Lake	7:30 PM ET	Philadelphia Union
Sat, Oct 10	NY Red Bulls vs. San Diego FC	7:30 PM ET	San Diego FC
Sat, Oct 10	Orlando SC vs. Columbus Crew	7:30 PM ET	The Draw
Sat, Oct 10	Charlotte FC vs. FC Dallas	7:30 PM ET	Charlotte FC
Sat, Oct 10	Atlanta United vs. FC Cincinnati	7:30 PM ET	SEE ABOVE
Sat, Oct 10	Austin FC vs. Nashville SC	8:30 PM ET	The Draw
Sat, Oct 10	Minnesota United vs. Houston Dynamo	8:30 PM ET	Minnesota United
Sat, Oct 10	Sporting KC vs. Portland Timbers	8:30 PM ET	SEE ABOVE
Sat, Oct 10	Colorado Rapids vs. Portland Timbers	8:30 PM ET	Portland Timbers
Sat, Oct 10	LAFC vs. Vancouver Whitecaps	8:30 PM ET	LAFC
Sun, Oct 11	St. Louis SC vs. LA Galaxy	7:00 PM ET	St. Louis SC

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How to Bet On MLS This Weekend

These are the best sportsbooks for U.S. bettors to place wagers on the MLS today:

Sportsbook ratings

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