World Cup Qualifier: Uruguay vs. Argentina Odds, Preview, and Picks (Mar 21)

The top two nations in World Cup qualification will be in action on Friday, March 21, 2025, as Argentina and Uruguay lock horns. Argentina currently sit top of the standings after winning eight of their opening 12 matches, which currently gives them a five-point advantage over Uruguay at the summit.

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How To Watch

• When: Friday, March 21, 2025 at 8:30 PM ET
• Where: Centenario, Uruguay
• How To Watch: ESPN

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Odds

Match Result	Odds
Uruguay	+150
Draw	+187
Argentina	+230

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Event Preview

All attention will be on securing a place at next summer’s World Cup across South America this week, as the top two nations in the current standings collide.

Argentina have set a hot pace at the summit, winning eight of their 12 matches. That run of form ensures that they come into this round with a five-point advantage over their rivals this week.

However, they may not be as rock solid as the table suggests this week. Argentina will be without Lionel Messi in Uruguay, and the national side have dropped points in three of their last five matches, which includes two defeats over that sequence.

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The early signs under Marcelo Bielsa were incredibly promising for Uruguay, but there would have been massive disappointment last summer as they could finish no better than third at the Copa America.

Their poor run of form has continued into their qualification campaign in recent months after winning just once across their last five matches. But, they do come into this round after going three without a defeat.

Major confidence can also be taken from their performance in the latest round of internationals, as they played out a fine 1-1 draw on the road against Brazil. However, a defeat against the world champions could see them drop to as low as fourth this week.

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Uruguay vs. Argentina Picks

Both of these sides have questions to answer regarding their recent form. Therefore, the trend of recent draws when these sides collide could be one to consider, as a point will be regarded as a positive outcome for both nations in their quest to achieve qualification.

Free Pick:

• The Draw