Skip to content

Expert prediction

Italian Open: Carlos Alcaraz vs. Lorenzo Musetti Preview, Odds, Head to Head, Picks (May 16)

  • Nikola Velickovic
  • May 15, 2025 at 4:11 AM EDT

Pick rationale

Analysis & key factors

  • Alcaraz vs. Musetti odds see Alcaraz as the -330 favorite.
  • These two met in the Monte Carlo finals, when Alcaraz won 2-1.
  • Alcaraz leads 5-1 in H2H against Musetti.

This game promises to be fun because we have two excellent players clashing at the Foro Italico in Rome. Carlos Alcaraz faces the home crowd favorite, Lorenzo Musetti.

Check out: Jannik Sinner vs. Tomy Paul Preview, Odds, Head to Head, Picks (May 16) 

How to Watch

  • When: Friday, May 16, 7:30 am ET
  • Where: Foro Italico, Rome, Italy
  • How to Watch: Tennis Channel

Alcaraz vs. Musetti Odds

PlayerOddsTotal
Carlos Alcaraz-33021.5
Lorenzo Musetti+23021.5

Game Preview

Carlos Alcaraz beat Jack Draper 6-4, 6-4, avenging his defeat to this rival in the semis of the Indian Wells. With this triumph, he locked the No.2 seed at Roland Garros and posted his 13th win in the past 14 events.

Alcaraz had a tough path to the finals, beating Dusan Lajovic and Laslo Djere in the opening two rounds before dropping a set to Karen Khachanov in the fourth round. However, everything got back to normal against Draper.

On the other side, Lorenzo Musetti didn’t lose a single set at the Italian Open. One by one, he would beat Virtanen, Nakashima, Medvedev, and Zverev, though having plenty of problems against the German and spending 2 hours and 15 minutes on the court.

We have to say that Zverev’s first serve was awful, making just 59% of it. This allowed Musetti to be perfect on breakpoint chances, converting all three of them.

Alcaraz vs. Musetti Head to Head

Alcaraz defeated Musetti in Monte Carlo a few weeks ago, 2-1. 3-6, 6-1, 6-0. We saw Carlos’ hurricane after losing the opening set.

Overall, it’s 5-1 for the Spaniard, whose sole loss was in the Miami Open in 2024, on the hard surface.

Alcaraz vs. Musetti Predictions

Carlos looks well right now, and we saw that when he more or less routinely defeated Draper, who plays excellent tennis. Meanwhile, we can’t get rid of the impression that Musetti didn’t dictate the tempo against Zverev, yet used the rival’s mistakes. Because of all this, we pick Carlos Alcaraz to win this event.

  • Free Italian Open picks: Carlos Alcaraz wins

Tennis

More Predictions

Tennis Insight

WTA Finals 2026 Odds and Picks: Can Rybakina Cap Her Year at Indian Wells?

Best bet: Elena Rybakina to win the WTA Finals (+225) Value pick: Mirra Andreeva to win the WTA Finals (+600) Claim a 125% Bonus Up to $2,500 at BetUS The WTA Finals 2026 heads to Indian Wells, with the best eight players in the world chasing the biggest prize outside the majors from November 8 […]

Alex Dudley 4 min read

Tennis Insight

Shanghai Masters: Alexander Davidovich Fokina vs. Rafael Jodar Preview, Odds, Picks (Oct 18)

Quite the unexpected final takes place at the Rolex Masters in Shanghai this Sunday, as two Spaniards meet, Davidovich Fokina and Jodar. How to Watch Davidovich Fokina vs. Jodar Odds Player Odds Davidovich Fokina TBA Jodar TBA Match Preview Davidovich Fokina has already won one Asian Tour title. Lifting the title in Chengdu showed his […]

Nikola Velickovic 2 min read

Tennis Insight

Laver Cup 2026 Picks, Odds & Betting Preview (Sep 25-27)

High-quality tennis action is set for the United Kingdom at the end of September, as the 2026 edition of the Laver Cup will be staged at The O2 Arena. In the ninth edition of the men’s tournament, players from Europe will compete against a world team on the indoor hard court in England’s capital city. […]

Alex Dudley 3 min read

Tennis Insight

US Open Final: Alexander Zverev vs. Ben Shelton Preview, Odds, and Picks (Sep 13)

History could be made in the Men’s US Open Final on September 13, as Ben Shelton bids to become the first American man to win a Grand Slam in 23 years. However, Alexander Zverev will be a red-hot favorite at the tennis betting sites. A fascinating final in prospect awaits at Arthur Ashe Stadium, and you can […]

Alex Dudley 3 min read

Tennis Insight

US Open: Aryna Sabalenka vs. Elena Rybakina Preview, Odds, and Picks (Sep 12)

All eyes will be on Arthur Ashe Stadium on Saturday 12, as the Women’s US Open Final will be staged. Aryna Sabalenka will have her sights set on a three-peat, while Elena Rybakina will be aiming to celebrate moving to the top of the world rankings with a second Grand Slam of 2026. The tennis betting sites struggle […]

Alex Dudley 3 min read