Skip to content

Expert prediction

Jacksonville Jaguars vs Buffalo Bills Odds, and Picks (Oct 8)

  • Keith McCarthy
  • Oct 2, 2023 at 7:30 PM EDT

Market

Odds currently unavailable

No odds are available for this selection yet.

  • Jacksonville easily defeated the Falcons, 23-7, in London on Sunday.
  • The Bills surged past the 3-0 Dolphins, winning by a score of 48-20.
  • These two teams last met on November 7, 2021, in a game the Jaguars won 9-6.

With the NFL season is in full swing, let’s preview the upcoming Jaguars vs Bills AFC matchup. Jacksonville remains in London for their 2nd game, aiming to go 2-0 overseas, while Buffalo seeks to build momentum.


How to Watch

  • NFL Network

Preview

The Jaguars improved to 5-5 all time in London, hoping to push that record back above .500 this week. Their defense was very impressive against Atlanta. LB Josh Allen had his 2nd 3-sack game of the season, and now holds a tie for 1st in the NFL in overall sacks. 2022 1st-overall pick Travon Walker was also active, picking up a sack of his own. If their offense starts to heat up, Jacksonville will have a shot to win the AFC.

Buffalo dominated Miami last week, winning the game 48-20. It was an especially impressive performance for the defense. They managed to cool down a blistering hot Dolphins offense, while keeping up their own hot offensive play. Since losing to the Jets in Week 1, the Bills have outscored their opposition 123-33. Unfortunately, they also lost star CB Tre White to an achilles injury, casting a shadow over their victory.


Prediction

The Jaguars haven’t looked that great on offense yet this season, and face their toughest defensive test so far against Buffalo. That being said, they have a capable defense of their own and offensive assets that could break out at any time. The Bills showed they are susceptible to an upset in Week 1, but have looked really solid since then. I see this game being pretty close, but I’d ultimately take the Bills to win by a score.

NFL Picks:

  • Bills 26, Jaguars 20 ()

NFL

More Predictions

NFL Insight

NFL Week 9 Upsets: Commanders Nasty Underdogs, Cardinals and Raiders Defending the Spread

Week 9 of the 2026 NFL season features several situational spots where short underdogs hold tactical, scheduling, or matchup advantages. There aren’t as many choices as in previous rounds, but there’s still enough for us bettors to make some money. Here is one straight-up upset pick and two point-spread underdog picks, backed by key tactical […]

Nikola Velickovic 3 min read

NFL Insight

NFL Week 9 Player Props: Pitts to Score a TD, Flournoy Continues to Grow

NFL Week 9 player props are here. We’ve waited to see the situation regarding potential absences and injuries, and with game day just around the corner, it was time to unleash the best player prop picks for this round. We have three selections for our bettors, carefully picked and evaluated following a thorough process. After […]

Nikola Velickovic 2 min read

NFL Insight

Broncos vs. Panthers Week 9 Picks: Young’s Poor Protection Will Cost Carolina

Best bet: Broncos ATS pick: Broncos -2.5 Bet Broncos vs. Panthers at BetUS Denver Broncos (6-2) hit the road to face the Carolina Panthers (3-4) and continue their excellent run. The Panthers have been on the downhill lately and are under pressure to win this game and get back to the winning side. Stay with […]

Nikola Velickovic 2 min read

NFL Insight

Giants vs. Eagles Week 9 Picks: Rested Giants After a Win in Philly

Best bet: Giants ATS pick: Giants -3.5 Bet Giants vs. Eagles at BetUS NFC East is completely wild these days. The New York Giants (4-2-1) lead the group, while the Philadelphia Eagles (2-6) sit last. The home team is in huge trouble, having multiple stars out due to injuries. The Giants also have some absences, […]

Nikola Velickovic 2 min read

NFL Insight

Browns vs. Saints Week 9 Picks: Indoor Arena Will Create Problems for Cleveland

Best bet: Saints -1.5 Straight up pick: Saints moneyline Bet Cardinals vs Cowboys at BetUS Cleveland Browns (5-3) are still in the mix for the playoffs. However, they will need to win in New Orleans against the Saints (2-5). Browns are very light underdogs here, sitting at +100 before we started writing this article. We […]

Nikola Velickovic 2 min read