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Expert prediction

NFL Week 3: Packers vs. Browns Preview, Odds, Picks (Sep 21)

  • Nikola Velickovic
  • Sep 15, 2025 at 9:40 AM EDT
  • Packers vs. Browns total is set at 42.5 points.
  • Green Bay has won the last 4 meetings against the Cleveland Browns.
  • Browns were trashed in Baltimore, 41-17.

We haven’t seen these two teams meet often. But in the last four encounters, Green Bay got the win each time.

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How to Watch

  • When: Sunday, September 21, 1 pm ET
  • Where: Huntington Bank Stadium, Cleveland, Ohio
  • How to Watch: FOX

Packers vs. Browns Odds

TeamMoneylineSpreadTotals
Packers-450-8.542.5
Browns+340+8.542.5

Game Preview

Green Bay did well against the Commanders, beating the rivals on Thursday Night Football, 27-18. Even though they weren’t perfect and there were plenty of issues in their performance, the Packers had no problems against Washington.

Josh Jacobs had 84 rushing yards for a TD, while TE Tucker Kraft caught 6 passes for 124 yards and one TD too. Love ended the game with 292 passing yards and two TD passes. Micah Parsons posted 0.5 sacks and 3 QB hits.

The Browns’ defense fell apart in Baltimore, allowing 41 points. Myles Garrett had 1.5 sacks and 2 quarterback hits, but overall, Cleveland was outplayed in every possible aspect of the game. Not just in defense, but offense too.

Joe Flacco threw for 199 yards, but missed 20 passes, and had a pick with one touchdown. He also fumbled and lost one ball. Dillon Gabriel, a second-string QB, came off the bench to post a TD pass, and all three of his pass attempts were precise.

Packers vs. Browns Head to Head

The overall result in the series is 14-7 for the Packers, with the note that the Packers won the previous 4 events.

Packers vs. Browns Predictions

The Packers’ offense isn’t as good as it seems, but we think it is capable of being solid against the Browns. On the other side, Parsons and Gary should be enough to pressure and distract Flacco, whose age is clearly a problem.

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