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Expert prediction

NFL Week 4: Ravens vs. Chiefs Preview, Odds, Picks (Sep 28)

  • Nikola Velickovic
  • Sep 24, 2025 at 5:05 AM EDT
  • Ravens vs. Chiefs matchup is the biggest game of the week.
  • Chiefs won 6 of the last 7 head-to-head meetings.
  • Baltimore has the top offense in the league, scoring 37 points per game.

This matchup is already a classic with Lamar on one and Mahomes on the other side. Two quarterbacks that defined this NFL era.

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How to Watch

  • When: Sunday, September 28, 4:25 pm ET
  • Where: Arrowhead, Kansas City, Missouri
  • How to Watch: CBS

Ravens vs. Chiefs Odds

TeamMoneylineSpreadTotals
Ravens-150-2.548.5
Chiefs+130+2.548.5

Game Preview

The Ravens lost at home to the Lions on Monday Night Football 38-30. Baltimore’s O-line fell apart, having allowed 7 sacks on Lamar, who was beaten like never before. He had 3 touchdown passes and 288 passing yards.

Derrick Henry again fumbled, and he had just 50 rushing yards and a TD. Now, the Ravens’ defense didn’t produce a single sack, and that’s a huge problem. This team scores the most points in the NFL, 37, but allows the second-most, 32.

The Chiefs finally won. They beat the Giants on Sunday Night Football, 22-9. Mahomes had 224 passing yards, one TD pass, and Kansas City had two interceptions on Russell Wilson’s passes.

Andy Reid needs to improve his rushing because the team’s top runner is Mahomes with 125 yards. Now, knowing that he isn’t a Lamar type of player, that indicates problems in Kansas City’s offense.

Ravens vs. Chiefs Head to Head

Ravens lost 6 of the last seven games against the Chiefs. The previous game was the AFC Championship in 2024, which was played in Baltimore and ended in a 17-10 victory.

Ravens vs. Chiefs Predictions

Ravens have been relying on offense lately, while the Chiefs tend to play more defensive-minded games. Now, the way Ravens protect Lamar, he will get exposed a lot here. Still, we don’t think that the defenses will set the tone in this event, but rather the offenses.

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