EPL: Crystal Palace vs. Liverpool Picks, Odds, and Preview (Sep 27)

The runaway leaders in the Premier League are back in action on Sep 27, as Liverpool bid to record six straight victories when they take on Crystal Palace. However, Oliver Glasner’s side have already tasted victory against the Reds this season after winning the Community Shield to kick off the campaign. You can find the odds and our Crystal Palace vs. Liverpool picks here.

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How To Watch

• When: Saturday, September 27, 2025, at 10:00 AM ET
• Where: Selhurst Park, London, England
• How To Watch: NBC

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Crystal Palace vs. Liverpool Odds

Match Result	Odds
Crystal Palace	+285
The Draw	+285
Liverpool	-106

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Head-to-Head Record

Liverpool have a dominant record against Crystal Palace, winning nine of their last ten league away matches against the Eagles. Meanwhile, Palace have won just one of their last 16 EPL clashes with the Reds.

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Match Preview

It has been a dominant start to the 2025-26 Premier League season by the defending champions, and this weekend’s clash could see Liverpool move eight points clear at the summit. The Reds have started the season with five straight victories, which included a battling success in last weekend’s Merseyside derby against Everton.

Liverpool have won their opening six league matches at the start of a new season on five previous occasions; most recently in 2019-20. However, it could be worth noting that only two previous reigning champions have kicked off the campaign with wins in six straight matches.

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Crystal Palace also come into this round sporting an unbeaten record. The Eagles have made their best start to a new season since 1990-91 when they went ten without defeat. Oliver Glasner’s side will be full of confidence after recording victories in two of their last three matches, and a third win over that period could see them end the round as high as second.

Palace were clinical in last weekend’s victory against West Ham, with Tyrick Mitchell netting the winner with just over 20 minutes remaining. Their defensive approach and ability to play on the counter-attack will make for an interesting narrative for this weekend’s clash.

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Crystal Palace vs. Liverpool Picks

Two unbeaten sides go head-to-head in the Premier League this weekend, but it is hard to overlook Liverpool’s dominant record in this fixture. The Reds look good value to maintain their dominant sequence, but we could foresee both teams scoring at least once.

Free Picks:

• Liverpool (-106)