Expert prediction
NFL Week 6: Chargers vs. Dolphins Preview, Odds, Picks (Oct 12)
- Nikola Velickovic
- Oct 6, 2025 at 1:05 AM EDT
- Chargers vs. Dolphins odds favor the franchise from LA.
- The Miami Dolphins allow the most rushing yards in the league, 174.2 per game.
- Chargers have back-to-back losses.
LA Chargers opened the season well, but Najee Harris’ injury ruined everything for them. However, that’s not all, because the backup RB, Omari Hampton, is also injured and questionable for this game.
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How to Watch
- When: Sunday, October 12, 1 am ET
- Where: Hard Rock Stadium, Miami, Florida
- How to Watch: CBS
Chargers vs. Dolphins Odds
Game Preview
The good thing for the Chargers (3-2) is that they face one of the worst teams in the NFL. The bad news is that they might be without their backup RB, Omarion Hampton, who picked up an ankle injury against the Commanders.
Now, that’s a big deal because the Chargers rely heavily on running, and the upcoming rivals are the worst run-stopping team in the league. This was supposed to be a matchup that favors the LAC.
One of the coolest punt returns tds gets called back for a penalty a 10 point swing pic.twitter.com/kjDo1cQcJq
— ChargersMuse (@ChargersMuse) October 5, 2025
Miami (1-4) was trashing the Panthers in Charlotte, leading 17-0, only to end up on the losing side in the end. It was 27-24 for Carolina, with the Fins having one of the most humiliating run performances in years, making just 19 rushing yards on 14 carries.
Tua had 256 passing yards for 3 touchdowns, not committing a single turnover. WR Jaylen Waddle had 110 receiving yards and a touchdown, while TE Darren Waller had 78 receiving yards and one touchdown, too.
Chargers vs. Dolphins Head to Head
The Fins have a positive record, winning 20 games, while the Chargers have 17 triumphs.
Chargers vs. Dolphins Predictions
The Chargers don’t look well at all, and their balance in the game is disrupted with Harris’s absence. Still, we believe that their harsh defense might make a difference here and bring them a win.
- Free NFL Picks: Chargers win
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