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Expert prediction

NFL Week 10: New England Patriots vs. Tampa Bay Buccaneers Preview, Odds, Picks (Nov 9)

  • Nikola Velickovic
  • Nov 4, 2025 at 12:02 PM EST

Pick rationale

Analysis & key factors

  • Patriots vs. Buccaneers odds favor the hosts at -145.
  • New England’s run defense is No. 1 in the NFL, allowing 75.4 yards per game.
  • Baker Mayfield has just two intercepted passes this year.

This is a true test for both sides. The Pats are 7-2, while the Bucs sit at 6-2. Tampa Bay has injury problems, which are a bit bigger than those of the guests, who have also experienced huge setbacks.

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How to Watch

  • When: Sunday, November 9, 1 pm ET
  • Where: Raymond James Stadium, Tampa Bay, Florida
  • How to Watch: CBS

Patriots vs. Buccaneers Odds

TeamMoneylineSpreadTotals
Patriots+125+2.548.5
Buccaneers-145-2.548.5

Game Preview

Drake Maye is one of the contenders to win the NFL MVP accolades. This individual has an excellent campaign, boasting the fifth-most passing yards in the league, 2,285, with 17 touchdown passes and only 4 interceptions. Plus, he ran for 270 yards.

The Patriots’ defense allows 18.6 points per game and is the No. 1 against the run, allowing 75.4 yards per game. A very important part of the Pats’ game is exactly running, and they have three players with 270 or more yards on the ground. Besides Maye, Rhamondre Stevenson has 279, and TreVeyon Henderson recorded 283.

Buccaneers won’t have Mike Evans, who ended the year, but it’s possible to see Chris Godwin on the field again. The bye week came in the best possible moment for the Bucs, who were already feeling the consequences of injuries.

Baker Mayfield will have a huge help on the field now, as RB Bucky Irving returns to play. Irving was out, and until he picked up a foot injury, was one of the key players in Tampa Bay.

Patriots vs. Buccaneers Head to Head

The Pats have a 7-3 edge in the all-time series against the Buccaneers.

Patriots vs. Buccaneers Predictions

This one will be fire. We expect to see not just a good defense from the Patriots, but also from the Buccaneers, who had enough time to rest and scout their rivals properly. That’s why we go with Under 48.5 points.

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