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Expert prediction

NFL Week 15: Indianapolis Colts vs. Seattle Seahawks Preview, Odds, Picks (Dec 14)

  • Nikola Velickovic
  • Dec 10, 2025 at 6:04 AM EST
  • The Colts vs. Seahawks total is 42.5 points.
  • Phillip Rivers is coming out of retirement to play for the Colts.
  • The Seattle Seahawks are both the 2nd-best scoring attack and defense in the NFL

The Colts lost Daniel Jones, which is why Rivers had to get out of retirement. Meanwhile, the Seahawks are one of the best teams in the league and are massive favorites to win this event.

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How to Watch

  • When: Sunday, December 15, 4:25 pm ET
  • Where: Lumen Field, Seattle, Washington
  • How to Watch: CBS

Colts vs. Seahawks Odds

TeamMoneylineSpreadTotals
Colts+625+13.542.5
Seahawks-950-13.542.5

Game Preview

Many question Rivers’ ability to learn the scheme quickly, but just a few know that he, Shane Steichen, and Rivers have much deeper connections than assumed. Plus, they had regular contact in the past few months.

Jonathan Taylor will have to step up now, as he has only had one rushing touchdown in the past three games, combining for 217 rushing yards, fewer than he had in the NFL Berlin game when he ran 244 yards.

The Seahawks are excellent. Trashing the Falcons in Atlanta last weekend, 37-9, was impressive. They showed both aspects of play, both the defense and the offense, in the best possible shape.

Right now, this unit allows 17.4 points per game and scores 29.8 points per contest, both of which are the 2nd-best in the NFL. The Seahawks are 7-1 ATS in the last 8 and are also 7-1 straight up during the same period.

Colts vs. Seahawks Head to Head

There were 13 games between these teams in the past, and the Colts lead the series 7-6.

Colts vs. Seahawks Predictions

The Indianapolis Colts are in a tough spot, and undoubtedly, the Seahawks are going to take advantage of that. We expect to see them covering the spread without any problems here.

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