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Expert prediction

NFL Week 13: Jacksonville Jaguars vs. Tennessee Titans Preview, Odds, Picks (Nov 30)

  • Nikola Velickovic
  • Nov 25, 2025 at 6:58 AM EST

Pick rationale

Analysis & key factors

  • Jaguars vs. Titans total is 41.5 points
  • Total went over in 4 of the Titans’ last 5 events.
  • Jaguars have the best rush defense in the league, 83.8 points per game.

The upcoming AFC South matchup has tremendous value for the Jags, who have to win here. A triumph would keep them in the race for the division’s top, so there’s a lot of pressure on Trevor Lawrence and the guys.

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How to Watch

  • When: Sunday, November 30, 1 pm ET
  • Where: Nissan Stadium, Nashville, Tennessee
  • How to Watch: CBS

Jaguars vs. Titans Odds

TeamMoneylineSpreadTotals
Jaguars-320-6.541.5
Titans+260+6.541.5

Game Preview

Jags beat the Cardinals after overtime 27-24, keeping themselves in contention for the top spot in the AFC South. It was a huge victory for this unit, whose two of the past three triumphs came during OT. Cam Little won this one with a 52-yard FG.

Trevor Lawrence had another rollercoaster game, with 256 yards passed, three touchdowns, three interceptions thrown, and a fumble lost. Though the defense stepped up, having limited the Cards to 55 rushing yards and sacking Jacoby Brissett 6 times.

As for the Titans, they played okay against the Seahawks, losing 30-24, but couldn’t push harder to surprise one of the best teams in the NFC. Cam Ward had a couple of solid moves, ending the game with 256 passing yards for one touchdown pass, without a turnover.

The problem was the running, because Tennessee posted 64 rushing yards, of which Ward contributed with 37. Tony Pollard had 20 on 11 carries, and that’s terrible.

Jaguars vs. Titans Head to Head

The series result is 35-26 in favor of the Titans. Last year, the Jags won both games, 10-6 on the road and 20-13 at home.

Jaguars vs. Titans Predictions

The Jags have been solid these days, and they shouldn’t have any problems against the Titans, who are probably the weakest team in the NFL. Our pick here is Jacksonville to cover a 6.5-point spread.

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