Expert prediction
NFL Week 3: Dolphins vs. Bills Preview, Odds, Picks (Sep 18)
- Nikola Velickovic
- Sep 15, 2025 at 9:40 AM EDT
- Dolphins vs. Bills spread is -12.5 on Buffalo.
- The Bills won 13 of the last 14 games against the Dolphins.
- Dolphins allowed 33 points in each of their opening two games.
The AFC East rivalry between the Bills and the Fins has been a one-sided domination over the last few years. The way things stand ahead of this event, it should stay like that.
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How to Watch
- When: Thursday, September 18, 8:15 pm ET
- Where: Highmark Stadium, Buffalo, New York
- How to Watch: Prime Video
Dolphins vs. Bills Odds
Game Preview
The Fins had another terrible performance, losing to the Patriots at Hard Rock Stadium, 33-27. Tua was once again chaotic and disorganized when it mattered the most. He did collect 315 passing yards and some big plays with two touchdowns, but on the other hand, Tua had plenty of mistakes.
He was sacked five times and had one pick, making some poor decisions in the game’s final phase. Tyreek Hill had 109 receiving yards, while the entire Fins rushing core posted 61 running yards.
Tua threw an interception on this play 💀 pic.twitter.com/nPUlO7VSOE
— NFL Memes (@NFL_Memes) September 14, 2025
The Bills’ offense is on fire. After two opening games, the team has already scored 71 points. After beating the Ravens, 41-40, they defeated the Jets in New York, 30-10.
Josh Allen has 542 passing yards so far and two touchdown passes. Besides that, the reigning NFL MVP posted two rushing scores. Veteran DT Joey Bosa had a sack and two QB hits, proving that he’ll be a big addition to this roster.
Dolphins vs. Bills Head to Head
The Bills won 13 of the last 14 matches against the Dolphins. That’s enough said about their H2H record.
Dolphins vs. Bills Predictions
We expect nothing but the Bills’ pure domination. They are way better than the Fins, who could experience a big-time defeat, which would put additional pressure on Mike McDaniel.
- Free NFL picks: Bills -12.5
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