Expert prediction
NFL Week 5: 49ers vs. Rams Preview, Odds, Picks (Oct 2)
Pick rationale
Analysis & key factors
- 49ers vs. Rams is the NFL Week 5 Thursday Night Football.
- The total in this game is set at 47.5 points.
- The Rams are favorites at -225.
Banged-up Niners visit their NFC West rivals, the LA Rams, coming as underdogs in this one with a very shaky Brock Purdy, who is under heavy pressure to start playing at the expected level.
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How to Watch
- When: Thursday, October 2, 8:15 pm ET
- Where: SoFi Stadium, Los Angeles, California
- How to Watch: Prime Video
49ers vs. Rams Odds
Game Preview
Numerous injuries have hit the Niners, and according to the latest info, WR Ricky Pearsall and QB Brock Purdy are questionable for TNF. To be honest, Purdy’s absence won’t be felt that much, as he has constantly underachieved this year. In 4 matches, he has 4 touchdown passes and the same number of interceptions.
We’ll be straight with you; he isn’t the starter material, and without the team’s help, that’s visible. Mac Jones should be back; his numbers are way better, with 563 passing yards in two games, and 4 TD passes with one pick.
Rams bounced back following a loss in Philly, beating the best offense in the league until Week 4, the Indianapolis Colts, 27-20. Their defense forced three turnovers, with the safety Kam Curl recording two interceptions.
Meanwhile, Matt Stafford threw for 375 yards and 3 touchdowns, with his favorite target being WR Puka Nacua, who had one touchdown reception and an incredible 170 yards from 13 catches.
49ers vs. Rams Head to Head
After 152 games, the record is on San Francisco’s side, 78-71-3.
49ers vs. Rams Predictions
Whoever starts here for the Niners won’t be able to save them from an inevitable defeat. The Rams play at home, have a healthier squad, and simply look way better than the 49ers.
- Free NFL pick: LA Rams win
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