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Expert prediction

NFL Week 6: Seahawks vs. Jaguars Preview, Odds, Picks (Oct 12)

  • Nikola Velickovic
  • Oct 7, 2025 at 5:11 PM EDT
  • Seahawks vs. Jaguars game total is 46.5 points.
  • Jags’ Devin Lloyd leads the league with 4 interceptions so far.
  • Seattle has the 5th-best attack in the NFL, 29.2 points per game.

Jaguars are 4-1, but there are so many doubts revolving around this team. The Seahawks are on the rise and are battling for the NFC West title. All this promises an interesting clash in Florida.

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How to Watch

  • When: Saturday, October 12, 1 pm ET
  • Where: EverBank Stadium, Jacksonville, Florida
  • How to Watch: FOX

Seahawks vs. Jaguars Odds

TeamMoneylineSpreadTotals
Seahawks+105+1.546.5
Jaguars-125-1.546.5

Game Preview

The Seattle Seahawks lost at home to the Buccaneers, 38-35, after one hell of a fight in which Chase McLaughlin’s 39-yard field goal made the difference. It took place with the time expiring, which made it even tougher for the Seahawks.

This team has the No. 5 offense in the NFL, averaging 29.2 points per game. Though, on the other side, they are the third-best defense against running, allowing 83 yards per game on the ground.

The Jaguars squezzed out a win against the Chiefs on Monday Night Football, 31-28. Trevor Lawrence’s late run into the end zone brought the win, but to be honest, the defense made the difference in this one. Lawrence was unreliable and inconsistent as always, even though he had 54 rushing yards and two TDs.

Devin Lloyd has 4 interceptions this season, and one of them was against the Chiefs. He would make a 99-yard pick-six, arguably the play of the entire round.

Seahawks vs. Jaguars Head to Head

There were 9 games overall between the two franchises, and the Seahawks lead 6-3.

Seahawks vs. Jaguars Predictions

The total here is 46.5 points, and that’s too high for us, and here is why. Both Lawrence and Darnold are a bit inconsistent this year, while on the other hand, the defenses are stepping up all the time. Our gut tells us that the game will go Under, and we have to go with it.

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