Champions League: Newcastle vs. Barcelona Picks, Odds, and Preview (Sep 18)

The biggest club soccer competition on the planet returns for the 2025-26 season this week, as the League Phase of the Champions League gets underway. Blockbuster fixtures across Europe are scheduled for this week, including a clash between Newcastle vs. Barcelona. You can find the odds and picks here.

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How To Watch

• When: Thursday, September 18, 2025, at 3:00 PM ET
• Where: St. James’ Park, Newcastle, England
• How To Watch: CBS

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Newcastle vs. Barcelona Odds

Player	Odds
Newcastle	+208
The Draw	+268
Barcelona	+116

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Head-to-Head Record

This week’s Champions League clash between Newcastle and Barcelona is the fifth competitive meeting between the sides. Since winning the first clash between the teams in September 1997, Newcastle have suffered defeats in each of the last three meetings.

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Match Preview

Newcastle United make their return to the Champions League with a sensational clash against Barcelona on Thursday. The Magpies should be confident after gaining a recent win in the Premier League against Wolves. However, this is a much more challenging assignment than it was on Saturday against a relegation contender.

The Magpies have a consistent record against Spanish sides, winning six of their last eleven. That includes victories in each of the last three. However, Newcastle will need to be stronger in the Champions League than they were in their previous campaign, as they come into this opener after winning just one of their last eight in the competition.

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Barcelona have enjoyed an excellent start to the new domestic season, headlined by a stunning 6-0 victory over Valencia in La Liga on Sunday. The Spanish club have excelled in European matches against English teams in recent memory, winning 12 of their last 16 and scoring an average of 2.1 per game.

However, Barcelona were beaten on their last trip to the nation by Liverpool. Despite that, the Spanish champions haven’t suffered successive defeats in England since 2012. Based on their strong start to the season, they will be challenging to oppose this week.

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Newcastle vs. Barcelona Picks

A stunning atmosphere will await the players at St. James’ Park on Thursday, and Newcastle will be hopeful that it can aid their chances against a talented Barcelona. However, we find it incredibly challenging to overlook the prospect of an away win, especially considering their performances in the final third so far this term.

Free Picks:

• Barcelona (+116)