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Expert prediction

NFL Picks Week 8: Expert Predictions, Best Bets and Odds for Every Game

  • Nikola Velickovic
  • Oct 28, 2026 at 8:28 PM EDT

Pick rationale

Analysis & key factors

Best moneyline: Cowboys (-285) vs Cardinals

Best pick against the spread: Commanders -5.5 vs Eagles

Best total: Under 46.5, Falcons vs Buccaneers

Bet NFL Week 8 at BetUS

Week 8 of the 2026 NFL season runs from Thursday, October 29 to Monday, November 2. The Houston Texans, New York Giants, New Orleans Saints and San Francisco 49ers are all on bye, but there are still 14 games to bet on, and you can find all the latest NFL Week 8 odds here.

Thursday Night Football kicks things off at Lambeau Field, where the Packers host the Carolina Panthers. Sunday’s slate is headlined by an AFC heavyweight clash between the Ravens and Bills in Orchard Park and an NFC North battle between the Vikings and Lions, before the Commanders host the Eagles on Sunday Night Football. Week 8 wraps up on Monday Night Football, with the Seahawks hosting the Bears at Lumen Field.

Below you’ll find our best bets for the week, previews of the key games, and our picks for every matchup on the Week 8 slate.

Our Top Picks for Week 8

Best moneyline: Cowboys (-285) vs Cardinals. Arizona has the worst defense in the NFL, allowing 29.7 points per game, and Dallas comes in off a 38-21 win in Philadelphia.

Best pick against the spread: Commanders -5.5 vs Eagles. Philadelphia is without Jalen Hurts for the season and scores just 18.1 points per game, while Washington comes in rested off a bye.

Best total: Under 46.5, Falcons vs Buccaneers. Two run-first offenses meet two of the league’s best run defenses in a divisional game with plenty of pressure on both sides.

Key Game Breakdowns and Predictions

Ravens vs Bills Prediction & Odds

Kickoff: Sunday, Nov 1 Β· 1:00 PM ET Β· Highmark Stadium, Orchard Park, NY

Two AFC contenders meet in Western New York, and Baltimore now expects to have Lamar Jackson under center despite a growing injury list. Buffalo returns home after back-to-back road wins in which it was tested and came through both times. Jackson’s return makes the Ravens a tougher opponent, but he may not be at 100%, and at home, we like the Bills to win by more than a field goal.

  • Best bet: Bills -3

Vikings vs Lions Prediction & Odds

Kickoff: Sunday, Nov 1 Β· 1:00 PM ET Β· Ford Field, Detroit, MI

Minnesota arrives at 6-0 with the NFL’s best defense, but the offense hasn’t looked convincing in recent weeks. Detroit’s pass rush should get after Kyler Murray, and with Jared Goff and the offense playing well at home, we think the Lions can hand the NFC leaders their first loss of the season.

  • Best bet: Lions -3.5

Eagles vs Commanders Prediction & Odds

Kickoff: Sunday, Nov 1 Β· 8:20 PM ET Β· Northwest Stadium, Landover, MD Β· NBC

Washington hosts a Philadelphia team without Jalen Hurts, who is out for the season, and with Saquon Barkley struggling for form. Dan Quinn is under real pressure after a 1-4-1 start, and coming off a bye, this is the ideal chance for the Commanders to ease it on Sunday Night Football.

  • Best bet: Commanders -5.5

NFL Picks Week 8: Every Game

DateTime (ET)GamePick
Thu, Oct 298:15 PM ET Carolina Panthers at Green Bay PackersPackers -4.5
Sun, Nov 11:00 PM ET Atlanta Falcons at Tampa Bay BuccaneersUnder 46.5
Sun, Nov 11:00 PM ET Baltimore Ravens at Buffalo BillsBills -3
Sun, Nov 11:00 PM ET Cleveland Browns at Pittsburgh SteelersSteelers (-185)
Sun, Nov 11:00 PM ET Indianapolis Colts at Jacksonville JaguarsJaguars -7.5
Sun, Nov 11:00 PM ET Las Vegas Raiders at New York JetsOver 44.5
Sun, Nov 11:00 PM ET Minnesota Vikings at Detroit LionsLions -3.5
Sun, Nov 11:00 PM ET Tennessee Titans at Cincinnati BengalsBengals -10.5
Sun, Nov 11:00 PM ET Arizona Cardinals at Dallas CowboysCowboys -6
Sun, Nov 14:05 PM ET Los Angeles Chargers at Los Angeles RamsRams -6.5
Sun, Nov 14:25 PM ETKansas City Chiefs at Denver BroncosUnder 41.5
Sun, Nov 14:25 PM ETNew England Patriots at Miami DolphinsPatriots (-400)
Sun, Nov 18:20 PM ET Philadelphia Eagles at Washington CommandersCommanders -5.5
Mon, Nov 28:15 PM ET Chicago Bears at Seattle SeahawksBears (+146)

How to Bet on NFL Week 8

Ready to put our NFL Week 8 picks into action? These sportsbooks all accept US players, so simply sign up, fund your account and head to the sportsbook section to find the latest odds for every game this week. New players can also claim a welcome bonus on their first deposit.

Sportsbook ratings

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